- CAS
- Purity
- 621-03-4
- 99%
Quality products?make an important contribution to long-term revenue and profitability. High quality purity >99% 2-CYANOACETANILIDE 621-03-4 for sale
cyanoacetic acid
aniline
cyanoacetanilide
| Conditions | Yield |
|---|---|
|
cyanoacetic acid;
With
phosphorus pentachloride;
In
dichloromethane;
for 0.5h;
Reflux;
aniline;
In
dichloromethane;
for 2h;
Reflux;
|
92%
|
|
cyanoacetic acid;
With
phosphorus pentachloride;
In
dichloromethane;
for 0.5h;
Reflux;
aniline;
In
dichloromethane;
for 2h;
Reflux;
|
92%
|
|
cyanoacetic acid;
With
phosphorus pentachloride;
In
dichloromethane;
for 0.5h;
Heating / reflux;
aniline;
In
dichloromethane;
at 20 ℃;
for 2h;
Heating / reflux;
|
82%
|
|
With
dicyclohexyl-carbodiimide;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1h;
|
76%
|
|
cyanoacetic acid;
With
phosphorus pentachloride;
In
dichloromethane;
at 40 ℃;
for 0.5h;
aniline;
In
dichloromethane;
at 40 ℃;
|
68%
|
|
With
N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
dichloromethane;
at 20 ℃;
for 2h;
|
62%
|
|
With
N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine;
Yield given. Multistep reaction;
CH2Cl2, 1.) 30 min, 2.) 2 h;
|
|
|
With
diisopropyl-carbodiimide;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1h;
|
|
|
With
trichlorophosphate;
In
1,2-dichloro-ethane;
Reflux;
|
|
|
With
diisopropyl-carbodiimide;
In
tetrahydrofuran;
at 20 ℃;
for 5.25h;
|
11.9 g
|
|
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 20 ℃;
for 24h;
|
|
|
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 20 ℃;
for 24h;
|
|
|
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 20 ℃;
for 24h;
|
cyanoacetic acid
cyanoacetanilide
| Conditions | Yield |
|---|---|
|
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
|
46%
|
The CAS number of 2-CYANOACETANILIDE is 621-03-4.
More information of 2-CYANOACETANILIDE 621-03-4 are:
|
CAS?Number |
621-03-4 |
|
Density |
1.209g/cm3 |
|
Melting Point |
198-202 °C |
|
Boiling Point |
401.8°C at 760 mmHg |
|
Flash Point |
196.8°C |
|
Vapor Pressure |
1.15E-06mmHg at 25°C |
|
Refractive Index |
1.5570 (estimate) |
|
HS CODE |
2926909090 |
|
PSA |
52.89000 |
|
LogP |
1.61178 |
|
Pka |
-1.03±0.10(Predicted) |
Synonyms?for?2-CYANOACETANILIDE 621-03-4:Acetanilide,2-cyano- (6CI,7CI,8CI); (Phenylcarbamoyl)acetonitrile;2-Cyano-N-phenylacetamide; 2-Cyanoacetanilide; Cyanoacetic acid anilide;N-Phenylcyanoacetamide; NSC 6313; UP 590-1; a-Cyanoacetanilide
The chemical formula of ?2-CYANOACETANILIDE is?C9H8 N2 O which containing 9 Carbon atoms,8 Hydrogen atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??2-CYANOACETANILIDE?is 160.175.
InChI:InChI=1/C9H8N2O/c10-7-6-9(12)11-8-4-2-1-3-5-8/h1-5H,6H2,(H,11,12)
Relevant articles related to 2-CYANOACETANILIDE:
|
Article |
Source |
|
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma |
Liang, Xuewu,Sun, Chenxia,Li, Chunpu,Yu, Haolan,Wei, Xiaohui,Liu, Xuyi,Bao, Wei,Shi, Yuqiang,Sun, Xiaochen,Khamrakulov, Mirzadavlat,Yang, Chenghua,Liu, Hong , p. 9217 - 9237 (2021/07/20) |
|
Nickel-promoted oxidative domino Csp3-H/N-H bond double-isocyanide insertion reaction to construct pyrrolin-2-ones |
Wen, Li-Rong,Wang, Ning-Ning,Du, Wu-Bo,Ma, Qiang,Zhang, Lin-Bao,Li, Ming supporting information, p. 2895 - 2900 (2021/04/14) |
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