- CAS
- Purity
- 72-23-1
- 99%
Buy reliable Quality 11-DEHYDROCORTICOSTERONE 72-23-1 raw material with Honest Price
- Molecular Formula: C21H28 O4
- Molecular Weight: 344.451
- Vapor Pressure: 1.9E-13mmHg at 25°C
- Melting Point: 183.5°C
- Refractive Index: 1.4430 (estimate)
- Boiling Point: 530°C at 760 mmHg
- PKA: 12.95±0.10(Predicted)
- Flash Point: 288.4°C
- PSA： 71.44000
- Density: 1.21g/cm3
- LogP: 2.87490
11-DEHYDROCORTICOSTERONE(Cas 72-23-1) Usage
|
Definition |
ChEBI: An 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidised to give the corresponding ketone. |
InChI:InChI=1/C21H28O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-16,19,22H,3-8,10-11H2,1-2H3/t14-,15-,16+,19+,20-,21-/m0/s1
72-23-1 Relevant articles
Structure-dependent inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 activities by phthalates
Zhao, Binghai,Chu, Yanhui,Huang, Yadong,Hardy, Dianne O.,Lin, Shaoqiang,Ge, Ren-Shan
, p. 79 - 84 (2010)
Phthalates are diesters of phthalic acid...
Mass spectrometry imaging for dissecting steroid intracrinology within target tissues
Cobice, Diego F.,Logan MacKay,Goodwin, Richard J. A.,McBride, Andrew,Langridge-Smith, Patrick R.,Webster, Scott P.,Walker, Brian R.,Andrew, Ruth
, p. 11576 - 11584 (2014/01/06)
Steroid concentrations within tissues ar...
Efficient C-21 Deoxygenation of 21-Alkoxy-20-keto Corticoid Steroids with Trimethylsilyl Iodide in the Presence of Methanol
Nagaoka, Masao,Kunitama, Yurie,Numazawa, Mitsuteru
, p. 334 - 338 (2007/10/02)
Reaction of 21-alkyl ethers 1, 4-6, 8, a...
Regiospecific deoxygenation of the dihydroxyacetone moiety at C-17 of corticoid steroids with iodotrimethylsilane.
Numazawa,Nagaoka,Kunitama
, p. 3722 - 3726 (2007/10/02)
-
72-23-1 Process route
-
-
145-13-1
Pregnenolone
-
-
50-22-6
Corticosterone
-
-
72-23-1
11-dehydrocorticosterone
-
-
2394-23-2
19,21-dihydroxypregn-4-ene-3,20-dione
-
-
10385-97-4
18,21-dihydroxy-4-pregnen-3,20-dione
Conditions
| Conditions | Yield |
|---|---|
|
With
air; dibutyric cyclic AMP; enucleated male Sprague-Dawley rat adrenal glands after feeding for 72 h with 1 percent NaCl; NaHCO3 buffer;
at 37 ℃;
for 3h;
Product distribution;
tritium labeled study;
|
-
-
53-06-5
Cortisone
-
-
516-15-4
11-Ketoprogesterone
-
-
72-23-1
11-dehydrocorticosterone
Conditions
| Conditions | Yield |
|---|---|
|
With
trimethylsilyl iodide;
In
chloroform;
for 3h;
Ambient temperature;
|
10%
84% |
|
With
trimethylsilyl iodide;
In
chloroform;
for 2h;
Ambient temperature;
|
10%
84% |
|
With
trimethylsilyl iodide;
In
acetonitrile;
for 3h;
Ambient temperature;
|
27%
46% |
|
With
trimethylsilyl iodide;
In
acetonitrile;
for 3h;
Ambient temperature;
|
27%
46% |
72-23-1 Upstream products
-
516-15-4
11-Ketoprogesterone
-
1173-27-9
21-acetoxy-pregn-4-ene-3,11,20-trione
-
39703-68-9
rac -21-acetoxy-3,3-ethanediyldioxy-pregn-5-ene-11,20-dione
-
53-06-5
Cortisone
72-23-1 Downstream products
-
124113-69-5
1-(3,11,20-trioxo-pregn-4-en-21-yl)-pyridinium; toluene-4-sulfonate
-
116-56-3
11-dehydro-20-dihydrocorticosterone
-
92010-58-7
Δ4 -pregnen-21-ol-3,11,20-trione p-fluorobenzoate
-
129786-20-5
21-(Trityloxy)pregn-4-ene-3,11,20-trione