- CAS
- Purity
- 4897-25-0
- 99%
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Perfect Factory Offer Excellent quality 5-Chloro-1-methyl-4-nitroimidazole 4897-25-0 with Safe Shipping We provide high quality 5-Chloro-1-methyl-4-nitroimidazole (CAS 4897-25-0), at a very affordable prices to our customers.
5-Chloro-1-methyl-4-nitroimidazole is an intermediate in azathioprine synthesis, also present in the end product. It induced contact dermatitis in a man working on azathioprine synthesis. Cross reactivity is possible with imidazoles tioconazole, and econazole.
5-Chloro-1-methyl-4-nitroimidazole (CMNI) is suitable for use in the rapid mix experiments to investigate the mechanism of anomalous radiosensitization of mammalian cells by CMNI. It may be used in the synthesis of 5-aryl-1-methyl-4-nitroimidazoles, via Suzuki coupling with arylboronic acids, catalyzed by dichlorobis-(triphenylphosphine)palladium(II), K2CO3 and tetrabutylammonium bromide.
The CAS number of 5-Chloro-1-methyl-4-nitroimidazole is 4897-25-0.
More information of 5-Chloro-1-methyl-4-nitroimidazole 4897-25-0 are:
|
CAS?Number |
4897-25-0 |
|
Density |
1.65 g/cm3 |
|
Melting Point |
148-150 °C(lit.) |
|
Boiling Point |
362.3 °C at 760 mmHg |
|
Flash Point |
172.9 °C |
|
Vapor Pressure |
4.08E-05mmHg at 25°C |
|
Refractive Index |
1.5500 (estimate) |
|
HS CODE |
2933290090 |
|
PSA |
63.64000 |
|
LogP |
1.50490 |
|
Pka |
-1.37±0.61(Predicted) |
The chemical formula of?5-Chloro-1-methyl-4-nitroimidazole is C4H4ClN3O2 which containing 4 Carbon atoms,4 Hydrogen atoms,1 Chlorine atoms,3 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of 5-Chloro-1-methyl-4-nitroimidazole is 161.548
5-Chloro-1-methyl-4-nitroimidazole is an intermediate in azathioprine synthesis, also present in the end product. It induced contact dermatitis in a man working on azathioprine synthesis. Cross reactivity is possible with imidazoles tioconazole, and econazole.
InChI:InChI=1/C4H4ClN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3
Relevant articles related to 5-Chloro-1-methyl-4-nitroimidazole:
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Article |
Source |
|
Rational design of novel immunosuppressive drugs: Analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects |
Crawford, Duncan J. K.,Maddocks, John L.,Jones, D. Neville,Szawlowski, Paul , p. 2690 - 2695 (1996) |
|
Hetaryl imidazoles: A novel dual inhibitors of VEGF receptors I and II |
Kiselyov, Alexander S.,Semenova, Marina,Semenov, Victor V. , p. 1440 - 1444 (2007/10/03) |
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