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5-Chloro-1-methyl-4-nitroimidazole


  • CAS
  • Purity
  • 4897-25-0
  • 99%
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1.What is the 5-Chloro-1-methyl-4-nitroimidazole ?

5-Chloro-1-methyl-4-nitroimidazole is an intermediate in azathioprine synthesis, also present in the end product. It induced contact dermatitis in a man working on azathioprine synthesis. Cross reactivity is possible with imidazoles tioconazole, and econazole.

5-Chloro-1-methyl-4-nitroimidazole (CMNI) is suitable for use in the rapid mix experiments to investigate the mechanism of anomalous radiosensitization of mammalian cells by CMNI. It may be used in the synthesis of 5-aryl-1-methyl-4-nitroimidazoles, via Suzuki coupling with arylboronic acids, catalyzed by dichlorobis-(triphenylphosphine)palladium(II), K2CO3 and tetrabutylammonium bromide.

2.What is the CAS number for 5-Chloro-1-methyl-4-nitroimidazole ?

The CAS number of 5-Chloro-1-methyl-4-nitroimidazole is 4897-25-0.

More information of 5-Chloro-1-methyl-4-nitroimidazole 4897-25-0 are:

CAS?Number

4897-25-0

Density

1.65 g/cm3

Melting Point

148-150 °C(lit.)

Boiling Point

362.3 °C at 760 mmHg

Flash Point

172.9 °C

Vapor Pressure

4.08E-05mmHg at 25°C

Refractive Index

1.5500 (estimate)

HS CODE

2933290090

PSA

63.64000

LogP

1.50490

Pka

-1.37±0.61(Predicted)

3.What is the molecular formula of 5-Chloro-1-methyl-4-nitroimidazole ?

The chemical formula of?5-Chloro-1-methyl-4-nitroimidazole is C4H4ClN3O2 which containing 4 Carbon atoms,4 Hydrogen atoms,1 Chlorine atoms,3 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of 5-Chloro-1-methyl-4-nitroimidazole is 161.548

4.What is 5-Chloro-1-methyl-4-nitroimidazole(4897-25-0)used for?

5-Chloro-1-methyl-4-nitroimidazole is an intermediate in azathioprine synthesis, also present in the end product. It induced contact dermatitis in a man working on azathioprine synthesis. Cross reactivity is possible with imidazoles tioconazole, and econazole.

InChI:InChI=1/C4H4ClN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3

Relevant articles related to 5-Chloro-1-methyl-4-nitroimidazole:

Article

Source

Rational design of novel immunosuppressive drugs: Analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects

Crawford, Duncan J. K.,Maddocks, John L.,Jones, D. Neville,Szawlowski, Paul

, p. 2690 - 2695 (1996)

Hetaryl imidazoles: A novel dual inhibitors of VEGF receptors I and II

Kiselyov, Alexander S.,Semenova, Marina,Semenov, Victor V.

, p. 1440 - 1444 (2007/10/03)

5.Perfect Factory Offer Excellent quality 5-Chloro-1-methyl-4-nitroimidazole 4897-25-0 with Safe Shipping

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